Examples

Clinical trial advertising examples that pass review

Eight sample recruitment ads for different kinds of studies, each annotated with why it works for the IRB and for Meta, plus a recruitment flyer, an Instagram Stories ad, and before-and-after rewrites of ads that would be rejected. Use them as a starting point for your own IRB packet.

Updated October 2026By Ryan Hartfield, TrialFill
Before you start

What every example on this page has in common

The short version

Every ad below follows the same structure: it names the institution, says it is a research study, describes the study in plain language, gives an age range and one or two eligibility hints, states the time commitment, mentions compensation in one plain sentence (if the IRB allows it), and links to the study team's own screener. That structure comes from FDA guidance on recruiting study subjects and Meta's rule against implying a viewer's health condition. For the full picture of how recruitment advertising works, see clinical trial advertising.

Facebook and Instagram feed ads

8 clinical trial ad examples by study type

Each one is written for a fictional study at a fictional institution, Riverside University, so the structure is the focus rather than the brand.

RU
Riverside University Clinical Research Unit
Sponsored
Riverside University is looking for healthy adults ages 18 to 45 to take part in a research study of an investigational vaccine. The study includes six visits over four months at the Riverside campus. Compensation for time and travel is provided.
Healthy Volunteer Research Study
Healthy Adults 18 to 45 Needed
Riverside University. IRB #RU-2026-0112.
Learn more
Example 1

Healthy volunteers study ad

  • Healthy-volunteer studies can address the reader directly, because being healthy is not a personal health attribute.
  • The visit schedule is stated up front, so people who cannot commit screen themselves out.
  • Compensation is one plain sentence, never the headline.

Healthy-volunteer studies draw from a large audience, so a clear time commitment does most of the filtering.

RU
Riverside University Department of Psychiatry
Sponsored
Researchers at Riverside University are studying a new talk-therapy approach for adults ages 25 to 60 who have felt low or lost interest in daily activities for at least two months. The study includes eight weekly sessions, in person or by video, at no cost.
Mood and Well-Being Research Study
Adults 25 to 60 May Be Eligible
Department of Psychiatry. IRB #RU-2026-0348.
Learn more
Example 2

Behavioral health study ad

  • Describes the experience in everyday words rather than naming a diagnosis, and never says "you" next to it.
  • States that sessions cost nothing without calling it "free treatment."
  • The remote option widens the audience without a larger radius.

Mental health ads are especially prone to personal-attributes rejections on Meta. Third-person wording and a calm, non-clinical image matter most here.

RC
Riverside Children's Research Center
Sponsored
Riverside Children's Research Center is conducting a study for children ages 8 to 14 who have asthma. Parents and guardians can learn more about the study, which includes four visits over three months and a home breathing log. Families receive compensation for time and travel.
Childhood Asthma Research Study
For Parents of Children 8 to 14
Riverside Children's. IRB #RC-2026-0071.
Learn more
Example 3

Pediatric (to parents) study ad

  • Written to parents and guardians, and targeted to adults, which is what Meta and most IRBs expect for minors.
  • Names the condition about the child in the third person, not the reader.
  • Describes everything the family will be asked to do, including the home log.

Meta limits ad targeting for people under 18 to age and location, so pediatric ads always target parents.

RU
Riverside University Women's Health Research
Sponsored
Riverside University is conducting a research study on hot flashes and sleep in women ages 45 to 60 going through menopause. The study involves three clinic visits and a sleep tracker worn at home for four weeks. Compensation may be available.
Menopause and Sleep Research Study
Women 45 to 60 May Qualify
Women's Health Research. IRB #RU-2026-0220.
Learn more
Example 4

Women's health study ad

  • A life stage (menopause) plus an age range lets the right people recognize themselves without implying a diagnosis.
  • The wearable is mentioned, because surprises at the screening call cost inquiries.
  • An image of a woman in the age range, not a symptom or a clinic, keeps it approachable.

TrialFill's completed women's health campaign drew 1,782 study page visits from $1,000 in 30 days.

RU
Riverside University Memory Research Center
Sponsored
The Riverside University Memory Research Center is enrolling adults ages 60 to 85 for a study on memory and healthy aging. Participants complete memory activities and a brain scan over five visits. A study partner, such as a spouse or adult child, is asked to come to some visits.
Memory and Healthy Aging Research Study
Adults 60 to 85: Learn About This Study
Memory Research Center. IRB #RU-2026-0405.
Learn more
Example 5

Memory and aging study ad

  • Frames the study around healthy aging, which an IRB and Meta accept more readily than a diagnosis.
  • Calls out the study partner requirement, the most common reason memory-study inquiries fall through.
  • A larger, plain headline suits an older audience on Facebook.

Adult children sometimes see memory-study ads and share them with a parent, so the copy should make sense to both.

RU
Riverside University Diabetes Research Program
Sponsored
Riverside University is conducting a research study of an investigational medication for adults ages 30 to 70 with type 2 diabetes who take metformin. The study lasts six months and includes eight visits. Study-related care is provided at no cost.
Type 2 Diabetes Research Study
Now Enrolling Adults 30 to 70
Diabetes Research Program. IRB #RU-2026-0187.
Learn more
Example 6

Chronic disease study ad

  • Calls the product investigational, as FDA guidance expects.
  • Uses a current medication as an eligibility hint, which filters far better than the diagnosis alone.
  • "Study-related care at no cost" is accurate; "free treatment" would be sent back.

For drug trials, never name the investigational product unless the IRB has approved it in the ad.

RU
Riverside University Neurology Research
Sponsored
Riverside University researchers are studying how a structured exercise program affects balance and walking in adults ages 50 to 80 living with Parkinson's disease. The study includes twice-weekly sessions for 12 weeks at the campus wellness center.
Movement and Balance Research Study
Help Researchers Study Movement
Neurology Research. IRB #RU-2026-0263.
Learn more
Example 7

Neurology study ad

  • A contribution headline ("Help researchers…") can work well for communities that are motivated to advance research.
  • The time commitment is spelled out: twice a week for 12 weeks.
  • No promise that the program improves balance; that is the question being studied.

TrialFill's neurology campaigns averaged $0.37 per click across five rounds for the same research team.

RU
Riverside University Vaccine Research Clinic
Sponsored
Riverside University's Vaccine Research Clinic is enrolling adults ages 65 and older in a study of an investigational RSV vaccine. The study includes four visits over one year. Compensation for time and travel is provided.
RSV Vaccine Research Study
Adults 65+ Needed for Vaccine Study
Vaccine Research Clinic. IRB #RU-2026-0299.
Learn more
Example 8

Vaccine and prevention study ad

  • States clearly that the vaccine is investigational and does not suggest it will protect anyone.
  • A year-long study says so in the first lines, which saves the team screening calls.
  • Seasonal studies benefit from launching before the season starts, when people are paying attention.

Prevention studies recruit healthy people, so the copy can be more direct than treatment studies.

Riverside University, Riverside Children's Research Center, the studies, IRB numbers, and copy above are fictional and shown for illustration only.

Riverside University · Research StudyMenopause and Sleep Research Study
Researchers at Riverside University are studying hot flashes and sleep in women going through menopause.
  • Women ages 45 to 60
  • Three clinic visits over four weeks
  • A sleep tracker worn at home
  • Compensation for time and travel may be available
To learn more and see if you may be eligible, scan the code or call the study team at 555-010-0199.
PI: Dr. A. Morgan · IRB #RU-2026-0220QR code
Print

Clinical trial recruitment flyer example

  • The headline is the study name, not a question or a promise.
  • Eligibility and commitment are bullet points someone can read from across a waiting room.
  • A QR code goes to the same screener as the online ads, so every inquiry is tracked in one place.
  • The PI and IRB number sit in the footer, where many institutions require them.

IRBs review flyers in final form, including type size and layout, so submit the designed version, not just the text. Flyers have a place next to clinics and on campus, but they reach only people who walk past them; most studies pair them with Facebook ads.

Riverside University · Research
Healthy adults 18 to 45 needed
A research study of an investigational vaccine. Six visits over four months. Compensation for time and travel is provided.
IRB #RU-2026-0112
Learn more
Vertical

Instagram and Facebook Stories ad example

  • Stories and Reels are vertical and full screen, so each approved ad needs its own vertical version.
  • Fewer words than the feed ad: who, what, and the commitment, with the rest on the screener.
  • Text stays clear of the top and bottom of the screen, where Instagram places the profile name and reply bar.

The vertical version is a separate piece of creative. Include it in the IRB packet next to the feed version rather than cropping the approved feed image later.

Before and after

Clinical trial ads that would be rejected, rewritten

The same idea, written two ways. The first version of each would be sent back by the IRB, rejected by Meta, or both. The full rules are in the clinical trial advertising guidelines.

Rejected
Struggling with anxiety? You could get FREE treatment and $500!
  • "Struggling with anxiety?" implies the reader has a condition
  • "Free treatment" and a dollar amount as the hook
Rewritten
Riverside University is studying a new therapy approach for adults ages 21 to 55 who often feel worried or on edge. Eight weekly sessions at no cost. Compensation may be available.
  • Third person, everyday language
  • Accurate cost wording, compensation stated once
Rejected
Try the new breakthrough drug that's helping people with knee pain finally get relief.
  • "Breakthrough" and "finally get relief" imply effectiveness
  • "New drug" without saying it is investigational
Rewritten
Riverside University is conducting a research study of an investigational medication for adults ages 40 to 75 with knee osteoarthritis. The study includes five visits over 12 weeks.
  • Investigational, with no claim about results
  • Condition described in the third person
Rejected
Is your child always sick? Sign them up for our study today!
  • Implies a health condition about the viewer's family
  • Pressure ("today!") and no information to decide
Rewritten
Riverside Children's Research Center is conducting a study for children ages 2 to 6 who get frequent ear infections. Parents can learn more about the study and what it involves.
  • Addresses parents with information, not pressure
  • Describes the child's eligibility in the third person
Real campaigns

Examples of real clinical trial recruitment campaigns

The ads above are samples. These are real results from Meta campaigns TrialFill ran for University of Alabama at Birmingham research studies, built on the same structure. Study names are withheld until each research team approves publication.

Neurology study
$0.37

average cost per click across five campaigns for the same research team, 7,007 link clicks from $2,599

Women's health study
1,782

visits to the study page in 30 days from $1,000 in ad spend, $0.56 per visit

Adolescent epilepsy study
854

visits to the study page from $600 across two campaigns, $0.70 per visit

Every campaign is on the results page, and the cost benchmarks are in the clinical trial advertising cost guide.

Patterns

What successful clinical trial ads do

Lead with the institution

A university or hospital name in the first line is the strongest trust signal a recruitment ad has.

Qualify, don't persuade

An age range and one key criterion filter the audience better than any interest targeting can.

State the commitment

Visits, length, and anything done at home. Surprises at the screening call lose people.

Speak in the third person

Describe the study and who may be eligible; never tell the reader they have a condition.

Keep money in its place

Compensation as one plain sentence, if the IRB approves it. Never the headline.

Send people to your screener

Every ad, flyer, and Story points to the same study-team form, so inquiries stay with your team.

Common questions

Clinical trial ad example questions

A good clinical trial ad names the institution, says it is a research study, describes the purpose in plain language, gives a short eligibility summary such as an age range and one key criterion, states the time commitment, and links to the study team's screener. For example: "Riverside University is conducting a research study on hot flashes and sleep in women ages 45 to 60 going through menopause. The study involves three clinic visits. Compensation may be available."

Under FDA guidance, it should not claim or imply that the product being studied is safe or effective, call it a "new treatment" without saying it is investigational, promise "free treatment" when it only means participation costs nothing, or emphasize payment. On Facebook and Instagram, it also cannot say or imply that the viewer has a health condition, such as "Do you have diabetes?"

Yes. The condition or purpose of the research is one of the items FDA guidance says an ad may include. On Meta, the condition has to be described in the third person ("adults with type 2 diabetes") rather than attributed to the reader ("your diabetes").

Two to four approved variations is a practical starting point: for example, a plain research ad, a contribution ad, and an eligibility-first ad. All variations need IRB approval before they run, so submitting them together in one packet saves a second review.

Clean study-branded graphics, campus or clinic photos, or a person who matches the age range, shown in a neutral, everyday setting. Avoid images of symptoms, distress, injections, or before-and-after comparisons, and never put a payment amount on the image.

No. Riverside University, the studies, the IRB numbers, and the ad copy on this page are fictional, written to show the structure that passes IRB and Meta review. Real creative from TrialFill's client studies is shared on request with each research team's permission, and real campaign numbers are on the results page.

Sources

The rules these examples follow

These examples are illustrations, not legal or regulatory advice. Your IRB's written policies always take precedence.

  1. U.S. Food and Drug Administration. Recruiting Study Subjects: Guidance for Institutional Review Boards and Clinical Investigators. fda.gov
  2. Meta Transparency Center. Advertising Standards: Privacy Violations and Personal Attributes. transparency.meta.com
  3. TrialFill first-party campaign data, Meta campaigns for University of Alabama at Birmingham research studies, September 2023 to October 2026. trialfill.com/results

Want ads like these written for your study?

TrialFill writes recruitment ads from your approved materials, delivers the full set as an IRB-ready packet, and runs them on Facebook and Instagram. Tell us about your study and you'll have a recruitment plan back within one business day.

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